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所在位置:所有产品 > 抗体抗原 > 一抗 > F11抗体
F11抗体图片
产品货号:
Z16507
中文名称:
F11抗体
英文名称:
Anti-F11 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-F11 Antibody
指标别名F11;Coagulation factor XI;FXI;EC 3.4.21.27
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,ICC/IF,FCM,ELISA
基因名称F11
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human FXI/F11 recombinant protein (Position:K79-Q155).
实际分子量150KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa,one of the enzymes of the coagulation cascade.Like many other coagulation factors,it is a serine protease.In humans,Factor XI is encoded by the F11 gene.This gene encodes coagulation factor XI of the blood coagulation cascade.This protein is present in plasma as a zymogen,which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds.During activation of the plasma factor XI,an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains,resulting in activated factor XIa,a serine protease composed of two heavy and two light chains held together by disulfide bonds.This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX.Defects in this factor lead to Rosenthal syndrome,a blood coagulation abnormality.
Uniprot IDP03951
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot.
基因名全称coagulation factor XI
蛋白名全称Coagulation factor XI
推荐稀释比
Western blot(WB) 1:500~2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
ELISA 1:100~1000

相关搜索:F11抗体F11多抗Anti-F11 Antibody
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